Klotho

*Coming Soon

Sharper Thinking, Healthier Aging

Enhance Cognitive Performance
Promote Healthy Aging
Support Cellular Resilience
Improve Long-Term Vitality
Woman resting her chin on her hand by a window

What Is Klotho?

Klotho is often called one of the body's longevity proteins because of its role in healthy aging and cognitive function.

As we age, natural Klotho levels decline. Gene expression therapy is designed to temporarily help your cells produce more Klotho protein, supporting cognitive performance, cellular resilience and long-term health without permanently changing your DNA.

How It Works

Klotho gene expression therapy uses a non-viral DNA platform to temporarily introduce new genetic instructions into your cells.

Those instructions allow your body to produce additional Klotho protein while remaining outside your chromosomes, meaning your DNA is never permanently altered.

Designed to:

Support

cognitive function

Promote

healthy aging

Enhance

cellular resilience

Remain

temporary and repeatable

Treatment at a Glance

Administration

Simple subcutaneous injection.

No surgery.

No hospitalization.

Duration

Designed to last approximately one year before treatment may be repeated.

Recovery

No downtime.

Most members return to normal activities immediately.

Man relaxing in a stone bath with ice on his shoulder

Availability

Coming Soon

Klotho is expected to become available to
House of Evolution members following its planned release.

Join the waitlist to receive priority access
as soon as appointments begin.

Explore the Science

Cover page of the Klotho and Follistatin study

Klotho &
Follistatin

2026 Preliminary Findings

Read Study
Cover page of the Follistatin gene expression therapy study

Follistatin Gene Expression Therapy

One-Year Human Study

Read Study
Cover page of the body composition and epigenetic age study

Body Composition & Epigenetic Age Study

Read Study

Be Among the First

Klotho represents one of the most promising frontiers in longevity science.

Apply for Access

Frequently Asked Questions

How is Klotho administered?

Through a simple subcutaneous injection performed by licensed medical professionals.

Does it permanently change my DNA?

No. The therapy uses non-viral gene expression technology that remains outside your chromosomes and does not permanently alter your DNA.

How long do the effects last?

The therapy is designed to provide temporary gene expression for approximately one year before treatment may be repeated.

When will Klotho become available?

House of Evolution members receive priority access as Klotho launches.